Home » Chronic Conditions » Ankylosing Spondylitis

Ankylosing Spondylitis

nurse consulting patient

What is Ankylosing Spondylitis?

Ankylosing spondylitis (AS) is a chronic condition and a form of arthritis that primarily causes inflammation in the spine. Over time, this inflammation can cause the small bones in your spine to fuse together, making your back less flexible and leading to a hunched posture. In severe cases, it may even restrict deep breathing if the ribs become affected.

This condition affects men more frequently than women, with signs usually appearing in early adulthood. Inflammation can also spread to other parts of your body, such as your eyes. Symptoms vary from person to person and might come and go, but common signs include:

  • Pain and stiffness in the lower back and hips, especially in the morning or after inactivity.
  • Neck pain and fatigue.
  • Pain that improves with exercise but worsens with rest.
  • Difficulty taking deep breaths.
  • Inflammation in the eyes that causes sensitivity to light or blurred vision.

Can You Prevent Ankylosing Spondylitis?

Unfortunately, you cannot prevent ankylosing spondylitis from starting. Scientists believe genetics play a major role, as many people with AS carry a specific gene called HLA-B27. 

However, simply carrying this gene does not guarantee you will develop the disease.

Although you can’t stop the condition from beginning, you can take steps to prevent damage. Early diagnosis helps slow the progression of the disease. Avoiding tobacco is vital because smokers with AS often face worse joint damage than non-smokers. Maintaining a healthy weight also reduces unnecessary stress on your painful joints.

Ankylosing Spondylitis Treatments

While there is no cure for AS, effective treatments reduce pain and prevent deformity. The main goal is to reduce inflammation to keep your spine healthy for as long as possible. Your doctor will create a personalized plan based on the severity of your condition.

Ankylosing Spondylitis Medications

Doctors often begin treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen and ibuprofen, to relieve inflammation, pain, and stiffness. If NSAIDs do not provide enough relief, your doctor might suggest biologics.

Biologics are stronger medications that target specific proteins in the body to stop inflammation. You typically receive these drugs through an injection or an IV infusion. 

TwelveStone Health Partners administers many of these therapies, including:

We provide a comfortable, private setting for these necessary treatments to help you manage your health.

nurse arms folded smiling

When to See a Rheumatologist

A rheumatologist specializes in arthritis and diseases of the joints, muscles, and bones. You should seek a referral if you experience specific warning signs, as early treatment leads to better long-term outcomes.

Consider seeing a specialist if your back pain developed slowly before age 45 or if morning stiffness lasts more than 30 minutes. You should also seek help if back pain wakes you up in the second half of the night or if the pain has persisted for more than three months. A family history of AS or psoriasis also warrants a visit to a specialist.

Contact TwelveStone Today!

Managing ankylosing spondylitis requires a trusted partner. TwelveStone Health Partners understands the complexities of chronic conditions. If your treatment plan includes infusion therapy or complex medication management, our team is here to help. We provide a safe, welcoming environment for your care. 

Contact us today to learn more about our services and how we support your journey toward better health.

Organizational Resources

The Spondylitis Association of America (SAA) has been the face, voice and leading nationwide nonprofit organization educating, empowering and advocating for people living with spondyloarthritis. 

Learn more

The National Ankylosing Spondylitis Society (NASS) is a voluntary, non-profit, self-help organization in the United Kingdom committed to providing information and support to affected individuals and family members.

Learn more

The Arthritis Foundation is a U.S. nonprofit organization that provides  information and resources, improves access to care, makes advancements in scientific research, and offers opportunities for community connections

Learn more

New Patient Resources